Major Findings: Neither aspirin nor a combination of aspirin and low-molecular-weight heparin improved live birth rates in a study of 364 women with unexplained recurrent miscarriages.
Data Source: The randomized placebo-controlled ALIFE study.
Disclosures: The ALIFE trial received funding from ZonMW, the Dutch Organization for Health Research and Development (945-27-003); an unrestricted grant from GlaxoSmithKline BV;and study medications (calcium carbasalate and placebo) from Vemedia BV. None of the funding sources were involved in the study protocol preparation, trial management, or data analysis, according to the abstract. Dr. Kaandorp had no financial disclosures. Dr. Middeldorp and another coinvestigator disclosed consultancy, honoraria, and research funding from GSK.
PREVIEW